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Faculty of Health Sciences
School of Medicine
Immunology
  
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Anderson, R
BSc(Hons)(Glasgow) MSc PhD(Witwatersrand) - Professor and Head

Contact details
Research interests
Research output

Contact details:

Telephone number: 012 319 2425
Fax number: 012 323 0732
E-mail address: randerso@medic.up.ac.za

Research interests:

Development of novel anti-tuberculosis chemotherapeutic agents

Development of novel anti-malaria chemotherapeutic agents

Novel derivatives with direct anti-cancer and multidrug-resistance neutralising properties

Pharmacological regulation of phagocyte activation in chronic inflammatory disorders

Oxidative stress

Tuberculosis

Investigation of the interactions of pneumolysin with human neutrophils in vitro

Research output:

Research articles in refereed specialist journals

Cockeran R, Steel HC, Mitchell TJ, Feldman C, Anderson R: 2001. Pneumolysin potentiates production of prostaglandin E2 and leukotriene B4 by human neutrophils. Infection and Immunity, 69(5)/May, pp 3494-3496.

Cockeran R, Theron AJ, Steel HC, Matlola NM, Mitchell TJ, Feldman C, Anderson R: 2001. Proinflammatory interactions of pneumolysin with human neutrophils. Journal of Infectious Diseases, 183/Feb, pp 604-611.

Feldman C, Anderson R, Theron AJ, Steel HC, Van Rensburg (Medlen) CEJ, Cole PJ, Wilson R: 2001. Vitamin E attenuates the injurious effects of bioactive phospholipids on human ciliated epithelium in vitro. European Respiratory Journal, 18, pp 122-129.

Matlola NM, Steel HC, Anderson R: 2001. Antimycobacterial action of B4128, a novel tetramethylpiperidyl-substituted phenazine. Journal of Antimicrobial Chemotherapy, 47, pp 199-202.

Peters EM, Anderson R, Nieman DC, Fickl H, Jogessar V: 2001. Vitamin C supplementation attenuates the increases in circulating cortisol, adrenaline and anti-inflammatory polypeptides following ultramarathon running. International Journal of Sports Medicine, 22, pp 537-543.

Peters EM, Anderson R, Theron AJ: 2001. Attenuation of increase in circulating cortisol and enhancement of the acute phase protein response in vitamin C-supplemented ultramarathoners. International Journal of Sports Medicine, 22, pp 120-126.

Tintinger GR, Theron AJ, Anderson R, Ker JA: 2001. The anti-inflammatory interactions of epinephrine with human neutrophils in vitro are achieved by cyclic AMP-mediated accelerated resequestration of cytosolic calcium. Biochemical Pharmacology, 61, pp 1319-1328.

Tintinger GR, Theron AJ, Steel HC, Anderson R: 2001. Accelerated calcium influx and hyperactivation of neutrophils in chronic granulomatous disease. Clinical and Experimental Immunology, 123, pp 254-263.

Chapters in books

Anderson R: 2001. Mechanisms of vitamin-mediated anti-inflammatory and immunomodulatory activity. , pp 135-147.

Feldman C, Anderson R, Theron AJ, Cole PJ, Wilson R: 2001. The Cytoprotective Effects of Macrolides, Azalides, and Ketolides on Human Ciliated Epithelium In Vitro. (14), pp 145-153.