Faculty of Health Sciences
School of Medicine
Department of Immunology
Anderson, R
BSc(Hons)(Glasgow) MSc PhD(Witwatersrand) - Professor and Head
Contact Details
Research Interests
Research Output
Contact Details:
Telephone number: 012 319 2425
Fax number: 012 323 0732
E-mail address: randerso@medic.up.ac.za
Research Interests:
Immunology/HIV
Tuberculosis: Development of novel anti-tuberculosis chemotherapeutic agents
Cancer: Novel derivatives with direct anti-cancer and multidrug-resistance neutralising properties
Pharmacological regulation of phagocyte activation in chronic inflammatory disorders
Oxidative stress
Investigation of the interactions of pneumolysin with human neutrophils in vitro
Research Output:
Research articles in refereed specialist journals:
Steel HC, Cockeran R, Anderson R: 2002. Platelet-activating factor and lyso-PAF possess direct antimicrobial properties in vitro. Acta Pathologica Microbiologica et Immunologica Scandinavica Section C - Immunology, 110, pp 158-164.
Steel HC, Anderson R: 2002. Dissociation of the PAF-receptor from NADPH oxidase and adenylate cyclase in human neutrophils results in accelerated influx and delayed clearance of cytosolic calcium. British Journal of Pharmacology, 136, pp 81-89.
Anderson R, Tintinger G, Feldman C: 2002. Regulation of calcium homeostasis in activated neutrophils and its relevance to inflammatory airway disorders. Clinical Pulmonary Medicine, 9, pp 159-165.
Cockeran R, Anderson R, Feldman C: 2002. The role of pneumolysin in the pathogenesis of Streptococcus pneumoniae infection. Current Opinion in Infectious Diseases, 15, pp 235-239.
Theron AJ, Steel HC, Tintinger GR, Anderson R: 2002. Endogenous adenosine regulates neutrophil pro-inflammatory activities by cyclic AMP-dependent accelerated clearance of cytosolic calcium. Inflammation Research, 51, pp 594-602.
Cockeran R, Durandt C, Feldman C, Mitchell TJ, Anderson R: 2002. Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro. Journal of Infectious Diseases, 186, pp 562-565.
Feldman C, Anderson R, Cockeran R, Mitchell TJ, Cole PJ, Wilson R: 2002. The effects of pneumolysin and hydrogen peroxide, alone and in combination, on human ciliated epithelium in vitro. Respiratory Medicine, 96, pp 580-585.
Tintinger GR, Anderson R, Ker JA: 2002. Regulation of calcium homeostasis in activated human neutrophils - potential targets for anti-inflammatory therapeutic strategies. South African Medical Journal, 92 (12), pp 990-996.
|
