Infiltration with Bleomycin of haemangioma and vascular malformation proved to be extremely successful with a significant response rate of 85% of patients. More than 50 patients (adults and children) have already been treated effectively. The research is genuine and has never been done so far. We set up a very sensitive method to determine the level of Bleomycin after intralesional injections at plasma and urine level. Thirty patients will be checked. The study will have two brances for comparison