Faculty of Health Sciences
School of Medicine
Department of Immunology
Theron, AJ
MSc PhD(Pret) - Associate Professor
Contact Details
Research Interests
Research Output
Contact Details:
Telephone number: 012 319 2623
Fax number: 012 323 0732
E-mail address: atheron@medic.up.ac.za
Research Interests:
Pharmacological regulation of phagocyte activation in chronic inflammatory disorders
Oxidative stress
Investigation of the interactions of pneumolysin with human neutrophils in vitro
Research Output:
Research articles in refereed specialist journals:
Oommen J, Steel HC, Theron AJ, Anderson R: 2004. Investigation into the relationship between calyculin A-mediated potentiation of NADPH oxidase activity and inhibition of store-operated uptake of calcium by human neutrophils. Biochemical Pharmacology, 68, pp 1721-1728.
Theron AJ, Ramafi GJ, Feldman C, Grimmer H, Visser SS, Anderson R: 2004. Effects of platinum and palladium on the production and reactivity of neutrophil-derived reactive oxygen-species. Free Radical Biology and Medicine, 36 (11), pp 1408-1417.
Cockeran R, Theron AJ, Feldman C, Mitchell TJ, Anderson R: 2004. Docosahexaenoic and eicosapentaenoic acid antagonize the proinflammatory interactions of pneumolysin with human neutrophils. Infection and Immunity, 72 (7) / July, pp 4327-4329.
Ramafi GJ, Theron AJ, Anderson R: 2004. Pro-oxidative interactions of cobalt with human neutrophils. Inhalation Toxicology, 16 (9) / Aug, pp 649-655.
Cockeran R, Theron AJ, Feldman C, Mitchell TJ, Anderson R: 2004. Pneumolysin potentiates oxidative inactivation of alpha-1-proteinase inhibitor by activated human neutrophils. Respiratory Medicine, 98, pp 865-871.
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