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Faculty of Health Sciences
School of Medicine
Department of Immunology

Anderson, R

BSc(Hons)(Glasgow) MSc PhD(Witwatersrand) - Professor and Head

Contact Details

Research Interests

Research Output

Contact Details:

Telephone number: 012 319 2425
Fax number: 012 323 0732
E-mail address: ronald.anderson@up.ac.za

Research Interests:

Tuberculosis: Development of novel anti-tuberculosis chemotherapeutic agents

Pharmacological regulation of phagocyte activation in chronic inflammatory disorders

Oxidative stress

Investigation of the interactions of pneumolysin with human neutrophils in vitro

Research Output:

Research articles in refereed specialist journals:

Tintinger GR, Anderson R: 2004. Counteracting effects of NADPH oxidase and the Na+/CA2+ exchanger on membrane repolarisation and store-operated uptake of Ca2+ by chemoattractant-activated human neutrophils. Biochemical Pharmacology, 67, pp 2263-2271.

Oommen J, Steel HC, Theron AJ, Anderson R: 2004. Investigation into the relationship between calyculin A-mediated potentiation of NADPH oxidase activity and inhibition of store-operated uptake of calcium by human neutrophils. Biochemical Pharmacology, 68, pp 1721-1728.

Steel HC, Anderson R: 2004. Itraconazole antagonizes store-operated influx of calcium into chemoattractant-activated human neutrophils. Clinical and Experimental Immunology, 136 (2) / May, pp 255-261.

Theron AJ, Ramafi GJ, Feldman C, Grimmer H, Visser SS, Anderson R: 2004. Effects of platinum and palladium on the production and reactivity of neutrophil-derived reactive oxygen-species. Free Radical Biology and Medicine, 36 (11), pp 1408-1417.

Cockeran R, Theron AJ, Feldman C, Mitchell TJ, Anderson R: 2004. Docosahexaenoic and eicosapentaenoic acid antagonize the proinflammatory interactions of pneumolysin with human neutrophils. Infection and Immunity, 72 (7) / July, pp 4327-4329.

Ramafi GJ, Theron AJ, Anderson R: 2004. Pro-oxidative interactions of cobalt with human neutrophils. Inhalation Toxicology, 16 (9) / Aug, pp 649-655.

Bopape C, Steel HC, Cockeran R, Matlola NM, Fourie PB, Anderson R: 2004. Antimicrobial activity of clofazimine is not dependent on mycobacterial C-type phospholipases. Journal of Antimicrobial Chemotherapy, 53, pp 971-974.

van Rooyen C, Anderson R: 2004. Assessment of determinants of optimum performance of the CASTŪ-2000 ELISA procedure. Journal of Immunological Methods, 288, pp 1-7.

Cockeran R, Theron AJ, Feldman C, Mitchell TJ, Anderson R: 2004. Pneumolysin potentiates oxidative inactivation of alpha-1-proteinase inhibitor by activated human neutrophils. Respiratory Medicine, 98, pp 865-871.

Meyer PWA, Brighton SW, Anderson R: 2004. Association of the HLA-DRB1*04 allele and its subtypes with rheumatoid arthritis in South Africa. South African Journal of Science, 100 (5/6) / May/Jun, pp 305-306.

Uys A, Rapoport BL, Anderson R: 2004. Febrile neutropenia: A prespective study to validate the Multinational Association of Supportive Care of Cancer (MASCC) risk-index score. Supportive Care in Cancer, 12 (8), pp 555-560.

 

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